Non-resolving pneumonia: A rare presentation of progressive disseminated histoplasmosis

Non-resolving pneumonia: A rare presentation of progressive disseminated histoplasmosis

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Histoplasmosis, a fungal disease caused by Histoplasma capsulatum, is endemic in North and South America.Except few scattered cases, the disease is considered to be a non-entity in India.Furthermore, disseminated histoplasmosis is rare in the immunocompetent individuals.We report an adolescent boy presenting as middle lobe consolidation Bike Parts - BMX - Handlebars which did not respond to antibiotics.His condition deteriorated with the development of mediastinal lymphadenopathy, pleural effusion and hepatosplenomegaly.

A diagnosis of progressive disseminated histoplasmosis was established by his clinical findings as well as bronchoscopic biopsy, transbronchial needle aspiration cytology and bronchoalveolar lavage culture demonstrating Histoplasma capsulatum.The case represents a unique example of progressive disseminated histoplasmosis in Pens and Markers an immunocompetent individual in India.